BAC to the future: functional genomics in mammals

Nat Methods. 2008 May;5(5):383-4. doi: 10.1038/nmeth0508-383.

Abstract

A high-throughput pipeline to engineer bacterial artificial chromosomes (BACs) expressing tagged genes of higher eukaryotes allows large-scale protein localization and interaction studies.

Publication types

  • Comment
  • News

MeSH terms

  • Animals
  • Chromosomes, Artificial, Bacterial / genetics*
  • Genetic Engineering / methods*
  • Genomics / methods*
  • Humans
  • Mammals / genetics*
  • Protein Binding
  • Transgenes / genetics