[Sclerochoroidal calcifications with vision-threatening choroidal neovascularisation]

Klin Monbl Augenheilkd. 2008 May;225(5):473-5. doi: 10.1055/s-2008-1027276.
[Article in German]

Abstract

Background: Sclerochoroidal calcification is an uncommon ocular condition in elderly patients. The lesions are frequently bilateral and located at the superotemporal quadrant. The diagnosis is made by fundoscopic appearance, angiography and echography.

History and signs: A 75-year-old man was referred with bilateral choroidal lesions and visual deterioration in the right eye. Examination revealed apart from old signs of a multifocal choroiditis also bilateral, elevated, yellow lesions located at the upper temporal arcades. In the right eye one lesion was accompanied by hemorrhages, edema and lipid exudates. A subsequent fluorescein angiography disclosed choroidal neovascularisation. Ultrasonography showed the characteristic findings of highly reflective lesions with acoustic shadowing. Serum calcium and phosphate levels were normal.

Therapy and outcome: Because of rapid visual deterioration on the right eye Ranibizumab (Lucentis) was injected intravitreal.

Conclusions: Despite their good prognosis, sclerochoroidal calcifications associated with neovascular membranes can become a vision-threatening disorder.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Angiogenesis Inhibitors / administration & dosage
  • Antibodies, Monoclonal / administration & dosage*
  • Antibodies, Monoclonal, Humanized
  • Calcinosis / complications
  • Calcinosis / drug therapy*
  • Choroidal Neovascularization / complications
  • Choroidal Neovascularization / drug therapy*
  • Humans
  • Male
  • Ranibizumab
  • Scleral Diseases / complications
  • Scleral Diseases / drug therapy*
  • Treatment Outcome
  • Vision Disorders / etiology
  • Vision Disorders / prevention & control*

Substances

  • Angiogenesis Inhibitors
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Ranibizumab