Synthesis, Characterization and In vitro Antitumour Activity of Novel Organotin Derivatives of 1,2- and 1,7-Dicarba-Closo-dodecaboranes

M Gielen; F Kayser; O B Zhidkova; V T Kampel; V L Bregadze; D de Vos; M Biesemans; B Mahieu; R Willem

doi:10.1155/MBD.1995.37

Synthesis, Characterization and In vitro Antitumour Activity of Novel Organotin Derivatives of 1,2- and 1,7-Dicarba-Closo-dodecaboranes

Met Based Drugs. 1995;2(1):37-42. doi: 10.1155/MBD.1995.37.

Authors

M Gielen¹, F Kayser, O B Zhidkova, V T Kampel, V L Bregadze, D de Vos, M Biesemans, B Mahieu, R Willem

Affiliation

¹ Free University of Brussels, VUB Department of General and Organic Chemistry Faculty of Engineering Room 8G512 Brussels Belgium.

Abstract

Several organotin derivatives of 1,2- and 1,7-dicarba-closo-dodecaboranes were synthesized and characterized by (119)Sn Mössbauer, (1)H, (13)C and (119)Sn NMR spectroscopy. Their antitumour activities in vitro against cancerous cell lines of human origin are reported.