Protein I of N. gonorrhoeae shows that phosphatidate from phosphatidylcholine via phospholipase C is an intracellular messenger in neutrophil activation by chemoattractants

Adv Prostaglandin Thromboxane Leukot Res. 1991:21B:545-52.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
  • 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / analogs & derivatives
  • 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / pharmacology
  • Bacterial Outer Membrane Proteins / isolation & purification
  • Bacterial Outer Membrane Proteins / pharmacology*
  • Diglycerides / analysis
  • Diglycerides / biosynthesis
  • Humans
  • Leukotriene B4 / pharmacology
  • N-Formylmethionine Leucyl-Phenylalanine / pharmacology*
  • Neisseria gonorrhoeae / analysis*
  • Neutrophils / drug effects*
  • Neutrophils / metabolism
  • Phosphatidic Acids / biosynthesis
  • Phosphatidic Acids / physiology*
  • Phosphatidylcholines / metabolism
  • Phospholipids / analysis
  • Porins
  • Receptors, Fc / physiology
  • Second Messenger Systems / physiology*
  • Type C Phospholipases / metabolism

Substances

  • Bacterial Outer Membrane Proteins
  • Diglycerides
  • Phosphatidic Acids
  • Phosphatidylcholines
  • Phospholipids
  • Porins
  • Receptors, Fc
  • Leukotriene B4
  • 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid
  • N-Formylmethionine Leucyl-Phenylalanine
  • Type C Phospholipases
  • 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid