Diffuse Lewy body disease presenting with a supranuclear gaze palsy

J Neurol Neurosurg Psychiatry. 1991 Feb;54(2):159-61. doi: 10.1136/jnnp.54.2.159.

Abstract

A patient with diffuse Lewy body disease presented with supranuclear vertical and horizontal ophthalmoplegia, dementia, axial rigidity and falls, bradykinesia and pyramidal signs. This broadens the clinical presentation of this pathological diagnosis and re-emphasises the heterogeneity of patients diagnosed clinically as progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome).

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cerebral Cortex / pathology*
  • Dementia / diagnosis*
  • Dementia / pathology
  • Diagnosis, Differential
  • Humans
  • Inclusion Bodies / ultrastructure*
  • Male
  • Neurofibrils / ultrastructure
  • Neurons / pathology
  • Neuropsychological Tests
  • Ophthalmoplegia / diagnosis*
  • Ophthalmoplegia / pathology
  • Parkinson Disease / diagnosis*
  • Parkinson Disease / pathology
  • Supranuclear Palsy, Progressive / diagnosis*
  • Supranuclear Palsy, Progressive / psychology