Follow-up of a multi-drug resistant HIV-1 infected patient successfully treated with darunavir and etravirine

J Med Virol. 2008 Aug;80(8):1319-21. doi: 10.1002/jmv.21226.

Abstract

A multi-drug-resistant, non-compliant HIV-1 patient was treated successfully with a combination of the drugs darunavir and etravirine for more than 8 months. The patient experienced an immunoreconstitution syndrome due to improved compliance. Examining previous resistance tests for this type of patient is valuable when assigning new medication.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-HIV Agents / pharmacology
  • Anti-HIV Agents / therapeutic use
  • Darunavir
  • Drug Resistance, Multiple, Viral*
  • Drug Therapy, Combination
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / immunology
  • HIV Infections / virology
  • HIV-1 / drug effects*
  • Humans
  • Microbial Sensitivity Tests
  • Nitriles
  • Patient Compliance
  • Pyridazines / pharmacology
  • Pyridazines / therapeutic use
  • Pyrimidines
  • Reverse Transcriptase Inhibitors / therapeutic use
  • Sulfonamides / pharmacology
  • Sulfonamides / therapeutic use
  • Treatment Outcome
  • Virus Replication / drug effects

Substances

  • Anti-HIV Agents
  • Nitriles
  • Pyridazines
  • Pyrimidines
  • Reverse Transcriptase Inhibitors
  • Sulfonamides
  • etravirine
  • Darunavir