[Clinical evaluation on fengweicao granule in treating benign prostatic hyperplasia]

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2008 May;28(5):456-8.
[Article in Chinese]

Abstract

Objective: To report the effect of Fengweicao Granule (FWCCG), a Chinese herbal preparation made of herba Pteris multifidae, in treating benign prostatic hyperplasia (BPH).

Methods: One hundred and fifty-five patients were assigned to two groups, the 108 patients in the treated group were administered orally with FWCG twice a day, 5 g every time; the 47 patients in the control group were treated with Proscar 5 mg per day for 3 months. The effects were evaluated by the change of the related indexes before and after treatment, including scoring by international prostatic symptom scale (I-PSS), maximum flowing rate of urine (MFR), residue urine volume (RU) in urinary bladder determined by abdominal B-ultrasonography and volume of prostate.

Results: After being treated for 3 months, the I-PSS, MFR and RU improved remarkably in both groups (P <0.05 or P <0.01), but with no significant change in the volume of prostate, neither with significant difference in comparison between the two groups (P >0.05).

Conclusion: FWCG has a good effect with less adverse reaction in treating BPH.

Publication types

  • Controlled Clinical Trial
  • English Abstract

MeSH terms

  • Diuresis / drug effects
  • Drugs, Chinese Herbal / therapeutic use*
  • Enzyme Inhibitors / therapeutic use
  • Finasteride / therapeutic use
  • Humans
  • Male
  • Medicine, Chinese Traditional
  • Prostatic Hyperplasia / drug therapy*
  • Pteris*

Substances

  • Drugs, Chinese Herbal
  • Enzyme Inhibitors
  • fengweicao
  • Finasteride