Cancer-suppressive effect of RNase A and DNase I

Dokl Biochem Biophys. 2008 May-Jun:420:108-11. doi: 10.1134/s1607672908030034.

Authors

O A Shklyaeva¹, N L Mironova, E M Malkova, O S Taranov, E I Ryabchikova, M A Zenkova, V V Vlasov

Affiliation

¹ Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, pr. Akademika Lavrent'eva 8, Novosibirsk, 630090 Russia.

PMID: 18680903
DOI: 10.1134/s1607672908030034

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antineoplastic Agents / administration & dosage
Antineoplastic Agents / metabolism
Antineoplastic Agents / pharmacology*
Antineoplastic Agents / therapeutic use
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Cell Proliferation / drug effects
Deoxyribonuclease I / administration & dosage
Deoxyribonuclease I / metabolism
Deoxyribonuclease I / pharmacology*
Deoxyribonuclease I / therapeutic use
Female
Lung Neoplasms / drug therapy
Lung Neoplasms / metabolism
Lung Neoplasms / pathology*
Lung Neoplasms / secondary
Mice
Mice, Inbred C57BL
Neoplasm Metastasis / prevention & control*
Nucleic Acids / metabolism
Ribonuclease, Pancreatic / administration & dosage
Ribonuclease, Pancreatic / metabolism
Ribonuclease, Pancreatic / pharmacology*
Ribonuclease, Pancreatic / therapeutic use

Substances

Antineoplastic Agents
Nucleic Acids
Deoxyribonuclease I
Ribonuclease, Pancreatic