Successful prevention of multidrug resistant HIV mother-to-child transmission with enfuvirtide use in late pregnancy

Int J STD AIDS. 2008 Sep;19(9):644-5. doi: 10.1258/ijsa.2008.008100.

Abstract

The availability of antiretroviral therapy has dramatically reduced the risk of HIV mother-to-child transmission (MTCT). However, mothers infected with multidrug resistant HIV (MDR-HIV) are at increased risk of MTCT. We report the case of a pregnant patient infected with MDR-HIV in whom MTCT was avoided with enfuvirtide use in late pregnancy and elective caesarean section.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • CD4 Lymphocyte Count
  • Cesarean Section*
  • Drug Resistance, Multiple, Viral*
  • Enfuvirtide
  • Female
  • HIV Envelope Protein gp41 / therapeutic use*
  • HIV Fusion Inhibitors / therapeutic use*
  • HIV Infections / drug therapy
  • HIV Infections / prevention & control
  • HIV Infections / transmission
  • Humans
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical / prevention & control*
  • Peptide Fragments / therapeutic use*
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy*
  • Treatment Outcome

Substances

  • HIV Envelope Protein gp41
  • HIV Fusion Inhibitors
  • Peptide Fragments
  • Enfuvirtide