Chronic myeloid leukemia in two patients with gastrointestinal stromal tumor

Int J Hematol. 2008 Oct;88(3):348-350. doi: 10.1007/s12185-008-0151-y. Epub 2008 Aug 29.

Authors

Erina Sakamoto¹, Tetsuji Sawada², Harushi Osugi³, Hirohisa Nakamae¹, Ki-Ryang Koh¹, Takahisa Yamane¹, Masahiko Ohsawa⁴, Kenichi Wakasa⁴, Masayuki Hino⁵

Affiliations

¹ Department of Clinical Hematology, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
² Department of Surgical Oncology, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
³ Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
⁴ Department of Diagnostic Pathology, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
⁵ Department of Clinical Hematology, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan. hinom@med.osaka-cu.ac.jp.

PMID: 18758897
DOI: 10.1007/s12185-008-0151-y

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Aged
Benzamides
Female
Fusion Proteins, bcr-abl
Gastrointestinal Stromal Tumors / drug therapy
Gastrointestinal Stromal Tumors / genetics
Gastrointestinal Stromal Tumors / metabolism*
Gastrointestinal Stromal Tumors / pathology
Genes, abl / genetics
Humans
Imatinib Mesylate
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / metabolism*
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology
Male
Middle Aged
Neoplasms, Second Primary / drug therapy
Neoplasms, Second Primary / genetics
Neoplasms, Second Primary / metabolism*
Neoplasms, Second Primary / pathology
Philadelphia Chromosome*
Piperazines / administration & dosage
Protein Kinase Inhibitors / administration & dosage
Protein Kinase Inhibitors / metabolism
Protein-Tyrosine Kinases / antagonists & inhibitors
Proto-Oncogene Proteins c-kit / genetics
Proto-Oncogene Proteins c-kit / metabolism
Pyrimidines / administration & dosage

Substances

Benzamides
Piperazines
Protein Kinase Inhibitors
Pyrimidines
Imatinib Mesylate
Protein-Tyrosine Kinases
Proto-Oncogene Proteins c-kit
Fusion Proteins, bcr-abl