In this article, we review the practical approach and diagnostic relevance of current seizure and epilepsy classification concepts and principles as a basic framework for good management of patients with epileptic seizures and epilepsy. Inaccurate generalizations about terminology, diagnosis, and treatment may be the single most important factor, next to an inadequately obtained history, that determines the misdiagnosis and mismanagement of patients with epilepsy. A stepwise signs and symptoms approach for diagnosis, evaluation, and management along the guidelines of the International League Against Epilepsy and definitions of epileptic seizures and epilepsy syndromes offers a state-of-the-art clinical approach to managing patients with epilepsy.