Primary Sjögren Syndrome with tumefactive central nervous system involvement

AJNR Am J Neuroradiol. 2008 Nov;29(10):1878-9. doi: 10.3174/ajnr.A1204. Epub 2008 Sep 10.

Abstract

Brain MR imaging abnormalities in primary Sjögren syndrome (pSS) are generally discrete white matter lesions. We describe a 50-year-old woman with recurrent neurologic deficits. MR imaging revealed a large brain lesion. A diagnosis of pSS was made on the basis of clinical features, positive anti-Ro and anti-La antibodies, abnormal Schirmer test findings, and salivary gland scintigraphy. The patient was treated with oral prednisone with good response. Large tumefactive brain lesions are a complication of pSS.

Publication types

  • Case Reports

MeSH terms

  • Brain Diseases / complications*
  • Brain Diseases / diagnosis*
  • Female
  • Granuloma, Plasma Cell / complications*
  • Granuloma, Plasma Cell / diagnosis*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Middle Aged
  • Sjogren's Syndrome / complications*
  • Sjogren's Syndrome / diagnosis*