Genetic characterisation of rabies virus isolates in Bosnia and Herzegovina

Bosn J Basic Med Sci. 2008 Aug;8(3):239-44. doi: 10.17305/bjbms.2008.2925.

Abstract

Serotyping of five rabies virus isolates with monoclonal anti-nucleoprotein antibodies for classical rabies virus and rabies-related viruses and phylogenetic relationships among sequences indicate that viruses circulating in population of animals in Bosnia and Herzegovina belong to the sero-genotype 1 of classical rabies virus. Phylogenetic relationships among sequences of our viruses have shown the presence of two phylogenetic lines, one which is present in the northwestern part and other which is present in the northeastern part of the country. Our viruses are closely related to Westeuropean isolates of rabies virus.

MeSH terms

  • Animals
  • Antibodies, Anti-Idiotypic / immunology
  • Base Sequence
  • Bosnia and Herzegovina / epidemiology
  • Cats
  • DNA, Viral / analysis
  • DNA, Viral / genetics
  • Dogs
  • Foxes
  • Genotype
  • Molecular Sequence Data
  • Nuclear Proteins / immunology
  • Phylogeny*
  • Rabies / epidemiology*
  • Rabies virus / classification*
  • Rabies virus / genetics*
  • Rabies virus / immunology
  • Serotyping

Substances

  • Antibodies, Anti-Idiotypic
  • DNA, Viral
  • Nuclear Proteins