Abstract
A 60-year old man was admitted with sepsis and meningitis of unknown aetiology. Underlying aortic valve endocarditis was diagnosed by echocardiography and severe insufficiency led to aortic valve replacement. Application of broad-range PCR to cusp tissue revealed a DNA product, and a diagnosis of Streptococcus pneumoniae endocarditis was obtained by DNA sequencing.
MeSH terms
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Aortic Valve Insufficiency / diagnostic imaging
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Aortic Valve Insufficiency / microbiology
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Aortic Valve Insufficiency / surgery
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Endocarditis, Bacterial / diagnosis
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Endocarditis, Bacterial / microbiology*
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Endocarditis, Bacterial / surgery
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Heart Valve Prosthesis
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Humans
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Male
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Middle Aged
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Pneumococcal Infections / diagnosis
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Pneumococcal Infections / microbiology*
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Polymerase Chain Reaction
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Streptococcus pneumoniae / genetics
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Streptococcus pneumoniae / isolation & purification
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Ultrasonography