Suppression of penicillin-induced lysis of Staphylococcus aureus by cibacron blue 3G-A

M Sugai; K Ooku; T Akiyama; S Inoue; S Iseda; Y Miyake; H Suginaka

doi:10.1016/0378-1097(91)90586-y

Suppression of penicillin-induced lysis of Staphylococcus aureus by cibacron blue 3G-A

FEMS Microbiol Lett. 1991 May 15;64(2-3):151-4. doi: 10.1016/0378-1097(91)90586-y.

Authors

M Sugai¹, K Ooku, T Akiyama, S Inoue, S Iseda, Y Miyake, H Suginaka

Affiliation

¹ Department of Microbiology, Hiroshima University School of Dentistry, Japan.

PMID: 1884976
DOI: 10.1016/0378-1097(91)90586-y

Abstract

The effect of cibacron blue 3G-A (CB) on bacteriolysis induced by penicillin G was investigated using Staphylococcus aureus FDA 209P. Penicillin-induced lysis was completely inhibited by 30 microM CB. However, the bactericidal effect of penicillin G was not influenced by CB. These results indicate that a bacteriolytic process is not essential for penicillin to kill S. aureus.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacteriolysis / drug effects*
Coloring Agents / pharmacology*
Penicillin G / pharmacology*
Staphylococcus aureus / drug effects*
Triazines / pharmacology*

Substances

Coloring Agents
Triazines
Cibacron Blue F 3GA
Penicillin G