Assessment of ovarian function with anti-Müllerian hormone in systemic lupus erythematosus patients undergoing hematopoietic stem cell transplant

Fertil Steril. 2009 Apr;91(4 Suppl):1529-32. doi: 10.1016/j.fertnstert.2008.08.123. Epub 2008 Oct 17.

Abstract

In this small pilot study, anti-Müllerian hormone (AMH) levels in women undergoing chemotherapy and hematopoietic stem cell transplantation facilitated earlier identification of impaired ovarian reserve compared with FSH and the resumption of menses. Larger studies are needed to accurately assess the clinical significance of AMH levels in the prediction of long-term reproductive outcomes in reproductive-age transplant patients with our current conditioning regimen.

Publication types

  • Research Support, N.I.H., Intramural

MeSH terms

  • Adolescent
  • Adult
  • Anti-Mullerian Hormone / blood*
  • Biomarkers / blood
  • Estradiol / blood
  • Female
  • Follicle Stimulating Hormone / blood
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Lupus Erythematosus, Systemic / blood*
  • Lupus Erythematosus, Systemic / surgery
  • Menstruation / physiology
  • Ovary / physiology*
  • Pilot Projects
  • Reproduction / physiology
  • Retrospective Studies
  • Sensitivity and Specificity
  • Young Adult

Substances

  • Biomarkers
  • Estradiol
  • Anti-Mullerian Hormone
  • Follicle Stimulating Hormone