[Combination chemotherapy with cisplatin and etoposide for cerebellar metastasis from ovarian adenocarcinoma]

No Shinkei Geka. 1991 Aug;19(8):751-4.
[Article in Japanese]

Abstract

A 54-year-old woman with cerebellar metastasis from ovarian adenocarcinoma was reported. Two years before admission, she underwent 7 courses of CAP therapy (cisplatin, adriamycin, cyclophosphamide) for ovarian cancer. On admission, no extracranial tumor was noticed. After the removal of a cerebellar tumor, she was treated by combination chemotherapy with cisplatin and etoposide. Her serum level of CA-125, which was still high after surgery, decreased to the normal level following chemotherapy. Chemotherapy was repeated six times, and no recurrence was noticed 1 year after surgery. Combination chemotherapy with cisplatin and etoposide was considered effective in the treatment of intracranial metastasis from ovarian cancer.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / secondary
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Cerebellar Neoplasms / drug therapy*
  • Cerebellar Neoplasms / secondary
  • Cisplatin / administration & dosage
  • Drug Administration Schedule
  • Etoposide / administration & dosage
  • Female
  • Humans
  • Infusions, Intravenous
  • Middle Aged
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery
  • Remission Induction

Substances

  • Etoposide
  • Cisplatin