Marginal excision of low-grade spindle cell sarcoma of canine extremities: 35 dogs (1996-2006)

Vet Surg. 2008 Jul;37(5):461-5. doi: 10.1111/j.1532-950X.2008.00408.x.

Abstract

Objective: To evaluate recurrence rate and disease-free interval (DFI) of dogs with low-grade soft tissue spindle cell sarcoma of the extremities treated by marginal excision.

Study design: Retrospective study.

Animals: Dogs (n=35) with soft tissue low-grade spindle cell sarcoma.

Methods: Medical records were reviewed and dogs that had marginal surgical resection of low-grade soft tissue spindle cell sarcoma at or distal to elbow and stifle were included.

Results: Histopathologic margins were dirty (12 dogs), clean but close (12), and clean (11). Follow-up after surgery occurred from 210 to 2202 days (minimum, 180 days). Local recurrence and metastatic rates were 10.8% and 0%, respectively. Median DFI and survival time were not reached, because <50% of dogs died of disease-related events. Mean DFI and mean survival time were 697.8 days (95% CI: 559.7-836 days) and 703.5 days (95% CI: 566.6-840.5 days), respectively. There were no significant differences among survival functions stratified by histologic margins.

Conclusion: Marginal surgical excision without adjuvant treatment of low-grade soft tissue spindle cell sarcoma of the extremities results in a low local recurrence rate.

Clinical relevance: Low-grade spindle cell sarcomas located at or distal to the elbow and stifle joints can be excised without need for wide or radical surgery.

MeSH terms

  • Animals
  • Dog Diseases / mortality*
  • Dog Diseases / pathology*
  • Dog Diseases / surgery
  • Dogs
  • Female
  • Follow-Up Studies
  • Kaplan-Meier Estimate
  • Male
  • Neoplasm Metastasis
  • Neoplasm Recurrence, Local / epidemiology
  • Neoplasm Recurrence, Local / veterinary
  • Neoplasm Staging / veterinary
  • Reoperation / veterinary
  • Retrospective Studies
  • Sarcoma / mortality
  • Sarcoma / pathology
  • Sarcoma / surgery
  • Sarcoma / veterinary*
  • Soft Tissue Neoplasms / mortality
  • Soft Tissue Neoplasms / pathology
  • Soft Tissue Neoplasms / surgery
  • Soft Tissue Neoplasms / veterinary*
  • Treatment Outcome