Flavone compound is a polyphenolic compound widely existing in plants and has an extensive biological activity. In recent years, it has been found to have a significant anti-cancer effect, as in combating cell proliferation, inducing cell apoptosis, interfering with cellular signal transduction, increasing the activity of the cancer repressor gene and inhibiting the expression of oncogene. This paper reviews the mechanism by which flavone compound, induces the apoptosis of prostate cancer cells.