Using a novel resource to decrease proteomic biomarker identification time

AMIA Annu Symp Proc. 2008 Nov 6:1033.

Abstract

The Empirical Proteomic Ontology Knowledge Base (EPO-KB) is an online database that represents current knowledge of biomarkers and contains associations between mass-to-charge (m/z) ratios of mass-spectrometry peaks to proteins. Such a database is a useful tool for identifying putative proteins associated with a m/z ratio. At present, EPO-KB contains data that have been extracted from 120 published research papers. It has been used in successful identification of a protein associated with a biomarker.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers / chemistry*
  • Databases, Protein*
  • Information Storage and Retrieval / methods*
  • Natural Language Processing*
  • Peptide Mapping / methods*
  • Proteome / chemistry*
  • Proteome / classification*
  • User-Computer Interface*

Substances

  • Biomarkers
  • Proteome