[Association of post transplantation diabetes mellitus to active human cytomegalovirus infection and preoperative hepatitis B virus infection: analysis of 75 cases]

Zhonghua Yi Xue Za Zhi. 2008 Jul 29;88(29):2053-5.
[Article in Chinese]

Abstract

Objective: To investigate the relationship of post transplantation diabetes mellitus (PTDM) to active human cytomegalovirus (HCMV) infection and to preoperative hepatitis B virus (HBV) infection respectively.

Methods: The clinical data of 75 patients with liver transplantation was collected to analyze the association of PTDM with active HCMV infection and preoperative HBV infection.

Results: The incidence of PTDM was 17.3% (13/75). The incidence of PTDM in the patients with active HCMV infection after liver transplantation was 23.1% (12/52) significantly higher than that of the patients without active HCMV infection (4.3%, 1/23, P < 0.05). The incidence of PTDM in the patients with preoperative HBV infection was 21.1%, not significantly different from that of the patients without infection (5.6%, P > 0.05).

Conclusion: PTDM may be related to active HCMV infection after liver transplantation, and unrelated to preoperative HBV infection.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • China / epidemiology
  • Cytomegalovirus Infections / epidemiology
  • Cytomegalovirus Infections / etiology*
  • Diabetes Mellitus / epidemiology
  • Diabetes Mellitus / etiology*
  • Female
  • Hepatitis B / epidemiology
  • Hepatitis B / etiology*
  • Humans
  • Incidence
  • Liver Transplantation / adverse effects*
  • Male
  • Middle Aged
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Young Adult