Coeliac disease, folic acid deficiency and epilepsy with cerebral calcifications

Acta Paediatr Scand. 1991 May;80(5):559-62. doi: 10.1111/j.1651-2227.1991.tb11906.x.

Abstract

Two cases of focal occipital epilepsy with cerebral calcifications poorly responsive to antiepileptic treatment are described. In both cases coeliac disease was diagnosed and folic acid deficiency documented. A gluten-free diet and a brief supplementation with folic acid lead to a complete EEG and clinical normalization in one case and to a significant improvement of EEG and seizure control in the other.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anticonvulsants / administration & dosage
  • Brain Diseases, Metabolic / diagnosis
  • Brain Diseases, Metabolic / etiology*
  • Brain Diseases, Metabolic / therapy
  • Calcinosis / diagnosis
  • Calcinosis / etiology*
  • Calcinosis / therapy
  • Celiac Disease / complications*
  • Celiac Disease / diagnosis
  • Celiac Disease / diet therapy
  • Child, Preschool
  • Epilepsies, Partial / diagnosis
  • Epilepsies, Partial / drug therapy
  • Epilepsies, Partial / etiology*
  • Female
  • Folic Acid / administration & dosage
  • Folic Acid Deficiency / diagnosis
  • Folic Acid Deficiency / diet therapy
  • Folic Acid Deficiency / etiology*
  • Glutens / administration & dosage
  • Humans
  • Occipital Lobe*

Substances

  • Anticonvulsants
  • Glutens
  • Folic Acid