Abstract
The establishment of (19)F NMR signal regulation and the application of this strategy to develop a multi-modal (19)F NMR probe for monitoring enzymatic activity using nanoparticles as a signal regulator is described; water-soluble perfluorinated cubic silsesquioxane was synthesized and immobilized onto the silica nanoparticles for suppressing the signals; (19)F NMR signals of the probes were recovered by releasing from nanoparticles.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaline Phosphatase / analysis*
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Alkaline Phosphatase / metabolism
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Fluorine Compounds / chemistry*
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Fluorine Radioisotopes
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Nanoparticles / analysis*
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Nanoparticles / chemistry*
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Organosilicon Compounds / chemistry*
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Silicon Dioxide / analysis*
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Silicon Dioxide / chemistry*
Substances
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Fluorine Compounds
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Fluorine Radioisotopes
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Organosilicon Compounds
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Silicon Dioxide
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Alkaline Phosphatase