Bile affects the synthesis of exopolysaccharides by Bifidobacterium animalis

Appl Environ Microbiol. 2009 Feb;75(4):1204-7. doi: 10.1128/AEM.00908-08. Epub 2008 Dec 16.

Abstract

By using cryo-scanning electron microscopy and quantification with lectin-conjugated probes, we have detected the production of exopolysaccharides (EPS) in Bifidobacterium animalis subsp. lactis in the presence of bile. In addition, the expression of gtf01207, which codifies a putative priming glycosyltransferase involved in EPS synthesis, was induced by bile.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / biosynthesis
  • Bifidobacterium / drug effects*
  • Bifidobacterium / metabolism*
  • Bifidobacterium / ultrastructure
  • Bile / metabolism*
  • Cryoelectron Microscopy
  • Gene Expression Profiling
  • Glucosyltransferases / biosynthesis
  • Lectins / metabolism
  • Molecular Sequence Data
  • Polysaccharides, Bacterial / biosynthesis*

Substances

  • Bacterial Proteins
  • Lectins
  • Polysaccharides, Bacterial
  • Glucosyltransferases

Associated data

  • GENBANK/EU651841
  • GENBANK/EU651842