Meiosis study in a population sample from Nigeria: allele frequencies and mutation rates of 16 STR loci

Carsten Hohoff; Marianne Schürenkamp; Bernd Brinkmann

doi:10.1007/s00414-008-0307-6

Meiosis study in a population sample from Nigeria: allele frequencies and mutation rates of 16 STR loci

Int J Legal Med. 2009 May;123(3):259-61. doi: 10.1007/s00414-008-0307-6. Epub 2009 Jan 21.

Authors

Carsten Hohoff¹, Marianne Schürenkamp, Bernd Brinkmann

Affiliation

¹ Institute of Legal Medicine, Münster University, Muenster, Germany.

PMID: 19156434
DOI: 10.1007/s00414-008-0307-6

Abstract

Allele frequencies for the 16 short tandem repeat (STR) loci D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, ACTBP2, CSF1PO, FGA, TH01, TPOX and VWA were determined for 337 immigrants from Nigeria. All loci were in Hardy-Weinberg equilibrium. More than 6,000 meiotic transfers were investigated and ten mutations were observed. Single mutations were observed in the STR systems D2S1338, D3S1358, D7S820, D8S1179, D16S539 and FGA, whereas two mutations were observed in the systems D21S11 and VWA.

MeSH terms

Adult
Black People / genetics*
Child
Chromosome Mapping*
DNA Fingerprinting
DNA Mutational Analysis*
Emigrants and Immigrants*
Female
Gene Frequency / genetics*
Genetics, Population*
Germany
Humans
Male
Meiosis / genetics*
Microsatellite Repeats / genetics*
Nigeria / ethnology