Propagation of sinusoidal electrical waves along the spinal cord during a fictive motor task

J Neurosci. 2009 Jan 21;29(3):798-810. doi: 10.1523/JNEUROSCI.3408-08.2009.

Abstract

We present for the first time direct electrophysiological evidence of the phenomenon of traveling electrical waves produced by populations of interneurons within the spinal cord. We show that, during a fictive rhythmic motor task, scratching, an electrical field potential of spinal interneurons takes the shape of a sinuous wave, "sweeping" the lumbosacral spinal cord rostrocaudally with a mean speed of approximately 0.3 m/s. We observed that traveling waves and scratching have the same cycle duration and that duration of the flexor phase, but not of the extensor phase, is highly correlated with the cycle duration of the traveling waves. Furthermore, we found that the interneurons from the deep dorsal horn and the intermediate nucleus can generate the spinal traveling waves, even in the absence of motoneuronal activity. These findings show that the sinusoidal field potentials generated during fictive scratching could be a powerful tool to disclose the organization of central pattern generator networks.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Action Potentials / physiology
  • Action Potentials / radiation effects
  • Animals
  • Autonomic Denervation / methods
  • Cats
  • Decerebrate State / pathology
  • Decerebrate State / physiopathology
  • Electric Conductivity
  • Electric Stimulation*
  • Electroencephalography / methods
  • Electromyography / methods
  • Interneurons / physiology
  • Motor Activity / physiology*
  • Neural Pathways
  • Periodicity
  • Skin / innervation
  • Spinal Cord / pathology*
  • Spinal Cord / physiopathology*