Dermatological side effects and complications of continuous subcutaneous insulin infusion in preschool-age and school-age children

Pediatr Diabetes. 2009 May;10(3):198-201. doi: 10.1111/j.1399-5448.2008.00477.x. Epub 2008 Nov 3.

Abstract

Objective: The objective of this study was to evaluate whether very young children develop more dermatological complications during insulin pump treatment compared with school children.

Study design: Cross-sectional study in 78 consecutive children using insulin pump treatment >4 months.

Results: Children in group A [n = 40, 28 males (M) and 12 females (F)] were 2.3 +/- 1.3 yr (+/-SD) and those in group B (n = 38, 13 M and 25 F) were 11.0 +/- 2.9 yr old at the start of continuous subcutaneous insulin infusion (CSII). The mean duration of CSII was similar in both groups (23.6 +/- 16.5 months in group A and 21.8 +/- 16.1 in group B). The most common dermatological complications were scars <3 mm (50% in group A vs. 71% in group B, p < 0.05) and lipohypertrophic areas at the insertion sites (45% in group vs. 47% in group B). Local abscesses and blisters were rare findings in both groups (7.5-12%), none leading to interruption or stop of CSII.

Conclusions: Dermatological side effects during CSII are not more frequent or severe in very young diabetic children compared with diabetic children in school age.

MeSH terms

  • Age Factors
  • Age of Onset
  • Aging
  • Anesthetics, Local / therapeutic use
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 1 / drug therapy*
  • Disinfectants / administration & dosage
  • Disinfection
  • Female
  • Humans
  • Insulin Infusion Systems / adverse effects*
  • Male
  • Parents
  • Patient Selection
  • Self Care
  • Skin Diseases / etiology*

Substances

  • Anesthetics, Local
  • Disinfectants