Coherent-pulse 2D crystallography using a free-electron laser x-ray source

Phys Rev Lett. 2009 Jan 23;102(3):035502. doi: 10.1103/PhysRevLett.102.035502. Epub 2009 Jan 22.

Abstract

Coherent diffractive imaging for the reconstruction of a two-dimensional (2D) finite crystal structure with a single pulse train of free-electron laser radiation at 7.97 nm wavelength is demonstrated. This measurement shows an advance on traditional coherent imaging techniques by applying it to a periodic structure. It is also significant that this approach paves the way for the imaging of the class of specimens which readily form 2D, but not three-dimensional crystals. We show that the structure is reconstructed to the detected resolution, given an adequate signal-to-noise ratio.

MeSH terms

  • Crystallography, X-Ray / instrumentation
  • Crystallography, X-Ray / methods*
  • Electrons
  • Image Processing, Computer-Assisted / methods
  • Lasers
  • Proteins / chemistry
  • X-Ray Diffraction / methods

Substances

  • Proteins