Getting under the skin of alternative splicing: identification of epithelial-specific splicing factors

Mol Cell. 2009 Mar 27;33(6):674-6. doi: 10.1016/j.molcel.2009.03.001.

Abstract

Alternative splicing patterns are regulated by factors that direct the activity of the spliceosome. In a recent issue of Molecular Cell, Warzecha et al. (2009) identify two new splicing regulators whose epithelial-specific expression induces several tissue-specific splicing events.

Publication types

  • Comment

MeSH terms

  • Alternative Splicing*
  • Epithelial Cells / metabolism*
  • Humans
  • RNA-Binding Proteins / genetics*
  • RNA-Binding Proteins / metabolism
  • Receptor, Fibroblast Growth Factor, Type 2 / genetics*
  • Receptor, Fibroblast Growth Factor, Type 2 / metabolism

Substances

  • ESRP1 protein, human
  • ESRP2 protein, human
  • RNA-Binding Proteins
  • FGFR2 protein, human
  • Receptor, Fibroblast Growth Factor, Type 2