Can local radiofrequency ablation of tumors generate systemic immunity against metastatic disease?

Radiology. 2009 Apr;251(1):1-2. doi: 10.1148/radiol.2511082215.

Abstract

Radiofrequency (RF) ablation may have the potential to turn a patient's tumor into an endogenous tumor vaccine; in this context of RF ablation-triggered immune system stimulation, the report by Dromi et al demonstrates a systemic immune response after local RF ablation in a mouse model.

Publication types

  • Comment

MeSH terms

  • Animals
  • Antigen Presentation / immunology*
  • Antigen-Presenting Cells / immunology*
  • Catheter Ablation*
  • Cell Line, Tumor
  • Humans
  • Immunity, Innate
  • Mice
  • Neoplasm Metastasis / immunology*
  • Neoplasm Metastasis / pathology
  • Neoplasm Metastasis / prevention & control*
  • Urinary Bladder Neoplasms / immunology*
  • Urinary Bladder Neoplasms / pathology
  • Urinary Bladder Neoplasms / surgery*