Abstract
The authors review the role played by mutations in mitochondrial DNA and in nuclear genes encoding mitochondrial proteins in cancer development, with an emphasis on the alterations of the oxidative phosphorylation system and glycolysis.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Cell Nucleus / genetics
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DNA, Mitochondrial / genetics*
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Glycolysis / genetics
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Humans
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Mitochondria / genetics*
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Mutation / genetics*
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Neoplasms / genetics*
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Oxidative Phosphorylation