Proliferative vitreoretinopathy: pathobiology and therapeutic targets

Yannek I Leiderman; Joan W Miller

doi:10.1080/08820530902800082

Proliferative vitreoretinopathy: pathobiology and therapeutic targets

Semin Ophthalmol. 2009 Mar-Apr;24(2):62-9. doi: 10.1080/08820530902800082.

Authors

Yannek I Leiderman¹, Joan W Miller

Affiliation

¹ Retina Service, The Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA. Yannek Leiderman@meei.harvard.edu

PMID: 19373688
DOI: 10.1080/08820530902800082

Abstract

The cell biology and molecular mediators of proliferative vitreoretinopathy continue to be elucidated. The purpose of this review is to summarize contemporary findings in the visual and neurosciences relevant to the pathophysiology of proliferative vitreoretinopathy, with an emphasis on the biologic mediators that represent potential therapeutic targets.

Publication types

Review

MeSH terms

Animals
Humans
Intercellular Signaling Peptides and Proteins / metabolism
Retinal Detachment / etiology
Vitreoretinopathy, Proliferative / complications
Vitreoretinopathy, Proliferative / etiology
Vitreoretinopathy, Proliferative / physiopathology*
Vitreoretinopathy, Proliferative / therapy*

Substances

Intercellular Signaling Peptides and Proteins