An atypical extrahepatic metastasis of the distal phalanx from hepatocellular carcinoma

Int J Clin Oncol. 2009 Apr;14(2):159-62. doi: 10.1007/s10147-008-0806-y. Epub 2009 Apr 24.

Abstract

A 49-year-old woman presented with severe swelling and pain of the left little finger, which had exacerbated rapidly, in October 2006. The patient had a history of hepatocellular carcinoma and metastatic lung cancer. She had undergone partial hepatectomy for the hepatocellular carcinoma in September 2001 and pulmonary resection for metastatic lung cancer in November 2005. Roentgenogram of the hand on admission showed complete destruction of the distal phalanx of the left little finger. The final pathological result of the tissue obtained by disarticulation was an extrahepatic metastasis of hepatocellular carcinoma. Extrahepatic metastasis from primary hepatocellular carcinoma to the hand is very rare and only four cases have been reported in the literature. All the patients with extrahepatic metastases from the primary hepatocellular carcinoma to the hand had poor prognoses, but the patient presented in this article exhibited an unusual clinical course. The patient is still alive 1 year after the diagnosis of extrahepatic bone metastasis of the distal phalanx.

Publication types

  • Case Reports

MeSH terms

  • Bone Neoplasms / diagnosis
  • Bone Neoplasms / secondary*
  • Carcinoma, Hepatocellular / mortality
  • Carcinoma, Hepatocellular / pathology*
  • Female
  • Finger Phalanges*
  • Humans
  • Liver Neoplasms / mortality
  • Liver Neoplasms / pathology*
  • Lung Neoplasms / secondary
  • Middle Aged
  • Survival Rate