Design, synthesis and pharmacological characterization of fluorescein-derived endothelin antagonists Bq-123 and Bq-788

Adv Exp Med Biol. 2009:611:443-4. doi: 10.1007/978-0-387-73657-0_191.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Drug Design*
  • Endothelin-1 / antagonists & inhibitors*
  • Molecular Sequence Data
  • Oligopeptides / chemical synthesis*
  • Oligopeptides / chemistry
  • Oligopeptides / pharmacology*
  • Peptides, Cyclic / chemical synthesis*
  • Peptides, Cyclic / chemistry
  • Peptides, Cyclic / pharmacology*
  • Piperidines / chemical synthesis*
  • Piperidines / chemistry
  • Piperidines / pharmacology*
  • Rabbits

Substances

  • Endothelin-1
  • Oligopeptides
  • Peptides, Cyclic
  • Piperidines
  • BQ 788
  • cyclo(Trp-Asp-Pro-Val-Leu)