[Effect of leukotriene receptor antagonist on cough variant asthma]

Nan Fang Yi Ke Da Xue Xue Bao. 2009 Apr;29(4):694-6.
[Article in Chinese]

Abstract

Objective: To study the curative effect of leukotriene receptor antagonist on cough variant asthma (CVA).

Methods: Sixty-four CVA patients received treatment with bricany and montelukas and 68 control patients had bricany treatment for 4 weeks. The recurrence rate was observed in the two groups during the follow-up for 6 months.

Results: The remission time of two groups were 2.5-/+3.6 and 5.3-/+3.8 days in acute phase, respectively, showing a significant difference between them (P<0.05). The recurrence rate of the two groups within 6 months were 20.09% and 40.87%, respectively, showing also significantly differences (P<0.05).

Conclusion: Leukotriene receptor antagonist and bricany can effectively control CVA and significantly lower the short-term recurrence rate of CVA.

Publication types

  • Clinical Trial
  • English Abstract

MeSH terms

  • Adult
  • Asthma / complications*
  • Asthma / drug therapy
  • Case-Control Studies
  • Cough / complications*
  • Cough / drug therapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Leukotriene Antagonists / adverse effects
  • Leukotriene Antagonists / pharmacology
  • Leukotriene Antagonists / therapeutic use*
  • Male
  • Receptors, Leukotriene / metabolism*
  • Recurrence

Substances

  • Leukotriene Antagonists
  • Receptors, Leukotriene