[The surgeon and anti-angiogenics]

J Soc Biol. 2009;203(2):193-5. doi: 10.1051/jbio/2009023. Epub 2009 Jun 16.
[Article in French]

Abstract

The surgeon must know the importance of angiogenesis in wound healing. He must also use anti-angiogenics to change the clinical situations and make curative a potentially ineffective surgery. However, these strategies require daily biological indicators able to quantify the tissue activity, that we do not possess yet, nor have we any indicator to predict tumour sensitivity to anti-angiogenics.

Publication types

  • Review

MeSH terms

  • Angiogenesis Inhibitors / administration & dosage
  • Angiogenesis Inhibitors / adverse effects
  • Angiogenesis Inhibitors / pharmacology
  • Angiogenesis Inhibitors / therapeutic use*
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / therapeutic use
  • Chemical and Drug Induced Liver Injury / etiology
  • Combined Modality Therapy
  • Drug Monitoring
  • General Surgery*
  • Humans
  • Liver Neoplasms / blood supply
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / surgery
  • Liver Regeneration / drug effects
  • Neoplasms / blood supply
  • Neoplasms / drug therapy
  • Neoplasms / genetics
  • Neoplasms / radiotherapy
  • Neoplasms / surgery*
  • Neovascularization, Pathologic / drug therapy*
  • Neovascularization, Pathologic / genetics
  • Neovascularization, Physiologic / drug effects*
  • Radiotherapy / adverse effects
  • Risk Assessment
  • Wound Healing / drug effects*

Substances

  • Angiogenesis Inhibitors
  • Antineoplastic Agents