Quality of life in treatment-seeking patients with obsessive-compulsive disorder with and without major depressive disorder

Can J Psychiatry. 2009 Jul;54(7):460-7. doi: 10.1177/070674370905400707.

Abstract

Objective: To compare the quality of life of patients with obsessive-compulsive disorder (OCD) with and without depression comorbidity.

Method: Treatment-seeking outpatients (n = 56) with OCD (n = 28) or comorbid OCD and major depressive disorder (MDD) (n = 28), matched by age, sex, and antidepressant medication use, completed a multidimensional measure of quality of life.

Results: Patients with comorbid OCD and MDD reported significantly greater decrements in their subjective feelings, social relations, and a composite measure of general activities (for example, overall well-being and life satisfaction) in comparison with patients with OCD without MDD. These differences were not owing to the presence of other Axis I comorbid disorders.

Conclusions: Treatments addressing depression comorbidity in the context of primary OCD are required to improve the quality of life of this severely affected population of OCD sufferers.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living / psychology
  • Adult
  • Combined Modality Therapy
  • Comorbidity
  • Cross-Sectional Studies
  • Depressive Disorder, Major / epidemiology
  • Depressive Disorder, Major / psychology*
  • Depressive Disorder, Major / therapy
  • Female
  • Hospitals, University
  • Humans
  • Interpersonal Relations
  • Male
  • Middle Aged
  • Obsessive-Compulsive Disorder / epidemiology
  • Obsessive-Compulsive Disorder / psychology*
  • Obsessive-Compulsive Disorder / therapy
  • Ontario
  • Patient Acceptance of Health Care / psychology*
  • Personal Satisfaction
  • Quality of Life / psychology*