Primary liposarcomas of the mediastinum are extremely rare. They have a dramatic clinical course. An unusual case of a giant primary liposarcoma of the mediastinum in a 49-year-old female is described. In spite of the tumor size the patient's only symptom was dry cough. Chest X-ray and CT showed a huge mass in the left pleural cavity. A radical procedure was performed with removal of a giant 25 x 31 cm soft fatty tumor. Pathology showed liposarcoma. The postoperative course was uneventful and follow-up examination after 12 months showed no recurrence of the disease.
Georg Thieme Verlag KG Stuttgart New York.