Total synthesis of pentabromo- and pentachloropseudilin, and synthetic analogues--allosteric inhibitors of myosin ATPase

Angew Chem Int Ed Engl. 2009;48(43):8042-6. doi: 10.1002/anie.200903743.
No abstract available

MeSH terms

  • Allosteric Regulation
  • Binding Sites
  • Catalysis
  • Computer Simulation
  • Crystallography, X-Ray
  • Cyclization
  • Dictyostelium / enzymology
  • Hydrocarbons, Chlorinated / chemical synthesis*
  • Hydrocarbons, Chlorinated / chemistry
  • Hydrocarbons, Halogenated / chemical synthesis*
  • Hydrocarbons, Halogenated / chemistry
  • Molecular Conformation
  • Myosins / antagonists & inhibitors*
  • Myosins / metabolism
  • Pargyline / analogs & derivatives
  • Pargyline / chemistry
  • Propylamines / chemistry
  • Pyrroles / chemical synthesis*
  • Pyrroles / chemistry
  • Silver / chemistry

Substances

  • Hydrocarbons, Chlorinated
  • Hydrocarbons, Halogenated
  • Propylamines
  • Pyrroles
  • pentabromopseudilin
  • pentachloropseudilin
  • tribromodichloropseudilin
  • tribromodifluoropseudilin
  • propargylamine
  • Silver
  • Pargyline
  • Myosins