The influence of artificial colonization with E. coli strain O83 on the intestinal flora in infants

Folia Microbiol (Praha). 1990;35(3):266-72. doi: 10.1007/BF02820494.

Abstract

Dominant bacterial strains present in stool (with particular emphasis on E. coli strains) were examined in 4 groups of healthy infants: breast-fed and bottle-fed, colonized with E. coli O83, and control (non-colonized) breast-fed and bottle-fed newborns. The presence of fimbriae was examined by hemagglutination, the P-fimbriae-bearing strains were tested by the PPA latex test. In addition, adherence to cell line HT-29 and serotyping was performed in selected strains. The E. coli strain O83 was found to possess type 1 fimbriae. Fewer bacterial strains possessing type 1 fimbriae were found in E. coli O83-colonized infants (except the O83 serotype) than in control infants. The E. coli O83 strain colonized significantly better the breast-fed than the bottle-fed infants; its higher adherence activity was demonstrated even in cell line HT-29. Finally, colonization with E. coli O83 influenced the character of microbial intestinal flora: the frequency of positive E. coli isolates was significantly higher in colonized (both breast- and bottle-fed) than noncolonized infants.

MeSH terms

  • Bacterial Adhesion
  • Bottle Feeding
  • Breast Feeding
  • Cell Line
  • Escherichia coli / classification
  • Escherichia coli / growth & development*
  • Escherichia coli / physiology
  • Fimbriae, Bacterial
  • Gram-Negative Bacteria / growth & development*
  • Hemagglutination Tests
  • Humans
  • Infant, Newborn
  • Intestines / microbiology*
  • Serotyping