Inhibition of Syk protein tyrosine kinase induces apoptosis and blocks proliferation in T-cell non-Hodgkin's lymphoma cell lines

Leukemia. 2010 Jan;24(1):229-32. doi: 10.1038/leu.2009.198. Epub 2009 Sep 24.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anaplastic Lymphoma Kinase
  • Apoptosis*
  • Cell Line, Tumor
  • Cell Proliferation
  • Humans
  • Intracellular Signaling Peptides and Proteins / antagonists & inhibitors
  • Intracellular Signaling Peptides and Proteins / physiology*
  • Lymphoma, T-Cell / pathology
  • Lymphoma, T-Cell / therapy*
  • Protein-Tyrosine Kinases / antagonists & inhibitors
  • Protein-Tyrosine Kinases / physiology*
  • RNA, Small Interfering / genetics
  • Receptor Protein-Tyrosine Kinases
  • Syk Kinase

Substances

  • Intracellular Signaling Peptides and Proteins
  • RNA, Small Interfering
  • Anaplastic Lymphoma Kinase
  • Protein-Tyrosine Kinases
  • Receptor Protein-Tyrosine Kinases
  • SYK protein, human
  • Syk Kinase