Chemotherapy: Irinotecan or etoposide as front-line therapy for SCLC?

Nat Rev Clin Oncol. 2009 Oct;6(10):562-3. doi: 10.1038/nrclinonc.2009.141.
No abstract available

Publication types

  • News

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B
  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / genetics
  • Antineoplastic Agents / therapeutic use
  • Antineoplastic Agents, Phytogenic / therapeutic use
  • Biological Transport / drug effects
  • Camptothecin / analogs & derivatives*
  • Camptothecin / metabolism
  • Camptothecin / pharmacokinetics
  • Camptothecin / therapeutic use
  • Carboplatin / pharmacokinetics
  • Carboplatin / therapeutic use
  • Cisplatin / therapeutic use
  • Clinical Trials, Phase III as Topic
  • Diarrhea / chemically induced
  • Drug Therapy / methods*
  • Drug Therapy, Combination
  • Enzyme Inhibitors / therapeutic use
  • Ethnicity / genetics
  • Etoposide / therapeutic use*
  • Female
  • Follow-Up Studies
  • Glucuronosyltransferase / genetics
  • Humans
  • Irinotecan
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / mortality
  • Lung Neoplasms / pathology
  • Male
  • Neutropenia / chemically induced
  • Polymorphism, Genetic
  • Randomized Controlled Trials as Topic
  • Small Cell Lung Carcinoma / drug therapy*
  • Small Cell Lung Carcinoma / mortality
  • Small Cell Lung Carcinoma / pathology
  • Survival Analysis
  • Therapeutic Equivalency
  • Time Factors
  • Treatment Outcome

Substances

  • ABCB1 protein, human
  • ATP Binding Cassette Transporter, Subfamily B
  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Antineoplastic Agents
  • Antineoplastic Agents, Phytogenic
  • Enzyme Inhibitors
  • Etoposide
  • Irinotecan
  • Carboplatin
  • UGT1A1 enzyme
  • Glucuronosyltransferase
  • Cisplatin
  • Camptothecin