CGS 18102A, a benzopyranopyridine anxiolytic with 5-HT1 agonist and 5-HT2 antagonist properties

Prog Clin Biol Res. 1990:361:469-75.
No abstract available

MeSH terms

  • 8-Hydroxy-2-(di-n-propylamino)tetralin
  • Animals
  • Anti-Anxiety Agents / pharmacology
  • Benzopyrans / pharmacology*
  • Binding, Competitive
  • Cerebral Cortex / metabolism
  • Ketanserin / antagonists & inhibitors
  • Ketanserin / metabolism
  • Kinetics
  • Piperidines / pharmacology*
  • Rats
  • Receptors, Serotonin / metabolism
  • Serotonin / metabolism
  • Serotonin / physiology
  • Serotonin Antagonists / metabolism
  • Serotonin Antagonists / pharmacology*
  • Tetrahydronaphthalenes / antagonists & inhibitors
  • Tetrahydronaphthalenes / metabolism

Substances

  • Anti-Anxiety Agents
  • Benzopyrans
  • Piperidines
  • Receptors, Serotonin
  • Serotonin Antagonists
  • Tetrahydronaphthalenes
  • CGS 18102A
  • Serotonin
  • 8-Hydroxy-2-(di-n-propylamino)tetralin
  • Ketanserin