Discovery and early development of squaraine rotaxanes

Chem Commun (Camb). 2009 Nov 14:(42):6329-38. doi: 10.1039/b911064j. Epub 2009 Aug 24.

Abstract

The chemical and photophysical properties of a fluorescent squaraine dye are greatly enhanced when it is mechanically encapsulated inside a tetralactam macrocycle. This feature article describes the synthesis, structure, and photophysical performance of first-generation squaraine rotaxanes, and shows how they can be used as fluorescent imaging probes and chemosensors.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Crystallography, X-Ray
  • Cyclobutanes / chemical synthesis
  • Cyclobutanes / chemistry*
  • Fluorescent Dyes / chemistry*
  • Mice
  • Mice, Nude
  • Molecular Conformation
  • Phenols / chemical synthesis
  • Phenols / chemistry*
  • Rotaxanes / chemical synthesis
  • Rotaxanes / chemistry*

Substances

  • Cyclobutanes
  • Fluorescent Dyes
  • Phenols
  • Rotaxanes
  • squaraine