FOXP3 forkhead domain mutation and regulatory T cells in the IPEX syndrome

N Engl J Med. 2009 Oct 22;361(17):1710-3. doi: 10.1056/NEJMc0907093.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abnormalities, Multiple / genetics*
  • Abnormalities, Multiple / immunology
  • Autoimmune Diseases / genetics
  • Fatal Outcome
  • Forkhead Transcription Factors / genetics*
  • Forkhead Transcription Factors / metabolism
  • Gene Expression Regulation
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Intestinal Diseases / genetics*
  • Intestinal Diseases / immunology
  • Male
  • Mutation, Missense*
  • Phenotype
  • Polyendocrinopathies, Autoimmune / genetics*
  • Polyendocrinopathies, Autoimmune / immunology
  • Syndrome
  • T-Lymphocytes, Regulatory*

Substances

  • FOXP3 protein, human
  • Forkhead Transcription Factors