Transcatheter closure of postsurgical residual ventricular septal defects: early and mid-term results

Catheter Cardiovasc Interv. 2010 Feb 1;75(2):246-55. doi: 10.1002/ccd.22262.

Abstract

Background: The incidence of residual ventricular septal defects (VSDs) after surgery is 5-25%. Redo surgery is associated with higher risks.

Methods: Between January 2000 to December 2008, 170 patients underwent percutaneous VSD closure in our centre: 22(16M) of these had 23 closures for residual VSDs. Median age was 32.5 yrs (1.4-79). All patients had echocardiographic signs of left ventricle volume overload (Q(p)/Q(s) >or= 1.5). Nine patients had previous VSD closure, 6 tetralogy of Fallot repair, and 7, other procedures. There were 15 muscular, 6 perimembranous and 2 apical VSDs.

Results: Amplatzer VSD devices were used in all. Median VSD size was 8 mm (4.3-16). Median fluoroscopy time was 33 minutes (15-130). There were three adverse events: 1 ventricular fibrillation requiring DC cardioversion; 1 transient complete atrio-ventricular block reverting to sinus rhythm at 24-hours; one patient had transient atrial flutter during the procedure. All procedures were successful; no additional procedures were required. Trivial residual shunts were seen in 3 patients at follow-up. There were no late events. One patient experienced arrhythmic death 5-yrs after procedure. One patient was reoperated due to dehiscence of VSD patch 2-yrs after the second successful percutaneous closure.

Conclusions: Transcatheter closure of postsurgical residual VSD is safe and efficacious management option and obviates the need for further surgery and by-pass.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cardiac Catheterization* / adverse effects
  • Cardiac Catheterization* / instrumentation
  • Child
  • Child, Preschool
  • Echocardiography, Transesophageal
  • Heart Septal Defects, Ventricular / diagnostic imaging
  • Heart Septal Defects, Ventricular / surgery
  • Heart Septal Defects, Ventricular / therapy*
  • Humans
  • Infant
  • Logistic Models
  • Middle Aged
  • Odds Ratio
  • Proportional Hazards Models
  • Prosthesis Design
  • Radiography
  • Reoperation
  • Risk Assessment
  • Septal Occluder Device
  • Time Factors
  • Treatment Outcome
  • Vascular Surgical Procedures* / adverse effects
  • Young Adult