Assessing autonomic symptoms of Parkinson's disease with the SCOPA-AUT: a new perspective from Rasch analysis

Eur J Neurol. 2010 Feb;17(2):273-9. doi: 10.1111/j.1468-1331.2009.02835.x. Epub 2009 Nov 12.

Abstract

Background: The Scale for Outcomes in Parkinson's disease (PD) for Autonomic Symptoms (SCOPA-AUT) is a specific scale to assess autonomic dysfunction in PD patients. It was developed and validated under the classic test theory approach. This study sought to test whether the SCOPA-AUT meets item response theory standards for reliability, internal construct validity, response category ordering, and differential item functioning by gender and age group.

Method: The Rasch measurement model was applied to a sample of 385 PD patients.

Results: Model fit was obtained after the response categories were rescored and item 10-Incomplete emptying deleted because of redundancy. Person separation index, a reliability measure, was 0.82. All but two items (2-Sialorrhea and 13-Nocturia) were free of gender- and age-related bias. The strict tests of unidimensionality were met, indicating the validity of the total sumscore. Scale targeting suggested the need for items representing milder autonomic symptoms.

Conclusions: Suggestions for improving the SCOPA-AUT include a shorter scale with a simpler response scheme and a combination of sexual items for men and women. The resulting SCOPA-AUT is a reliable scale, with good internal construct validity, providing Rasch transformed results on a linear metric scale.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Autonomic Nervous System Diseases / diagnosis*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Models, Theoretical
  • Parkinson Disease / diagnosis*
  • Reproducibility of Results
  • Severity of Illness Index*
  • Sex Factors