Abstract
Older adults carry the highest risk for coronary artery disease and the highest burden of atherosclerosis. Although most clinical trials of cholesterol-lowering therapy have not specifically targeted older persons, growing evidence supports treatment of elevated low-density lipoprotein cholesterol levels in older patients, especially those at high risk for coronary events. The decision to treat a high or high-normal cholesterol level in an elderly individual must be individualized based on chronologic and physiologic age. This article summarizes current data on lipid-lowering therapy in older adults and the management of hyperlipidemia in elderly patients.
MeSH terms
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Aged
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Anticholesteremic Agents / adverse effects
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Anticholesteremic Agents / therapeutic use*
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Cholesterol, LDL / blood
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Combined Modality Therapy
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Coronary Artery Disease / blood
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Coronary Artery Disease / epidemiology
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Coronary Artery Disease / prevention & control*
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Diet, Fat-Restricted
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Dietary Fiber / administration & dosage
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Exercise
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Humans
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Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects
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Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
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Hypercholesterolemia / blood
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Hypercholesterolemia / drug therapy*
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Hypercholesterolemia / epidemiology
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Life Style
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Randomized Controlled Trials as Topic
Substances
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Anticholesteremic Agents
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Cholesterol, LDL
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Dietary Fiber
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Hydroxymethylglutaryl-CoA Reductase Inhibitors