Re-irradiation of metastatic spinal cord compression: a feasibility study by volumetric-modulated arc radiotherapy for in-field recurrence creating a dosimetric hole on the central canal

Radiother Oncol. 2010 Jan;94(1):67-70. doi: 10.1016/j.radonc.2009.11.010. Epub 2009 Dec 18.

Abstract

When local recurrences arise within an irradiated region involving metastatic spinal cord compression, the dose limit to the spinal cord reduces the chance to re-treat the patient by 3D-conformational RT technique. The possibility of using volumetric modulated arc RT by RapidArc was evaluated for dose sparing at spinal cord level and preserving target coverage. A clinically satisfactory PTV coverage and dose sparing to the spinal cord were obtained. An upcoming trial on patients will provide clinical outcomes.

Publication types

  • Comparative Study

MeSH terms

  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Neoplasm Recurrence, Local / radiotherapy*
  • Radiometry
  • Retreatment
  • Spinal Cord Compression / etiology
  • Spinal Cord Compression / radiotherapy*
  • Treatment Outcome