Synthesis of functionalized maoecrystal V core structures

Chem Commun (Camb). 2010 Jan 7;46(1):70-2. doi: 10.1039/b917045f. Epub 2009 Oct 23.

Abstract

Two strategies toward the total synthesis of maoecrystal V (1) culminating in the construction of core structures 2 and 3 are described.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Crystallography, X-Ray
  • Diterpenes / chemical synthesis*
  • Diterpenes / chemistry
  • Diterpenes / toxicity
  • Drug Screening Assays, Antitumor
  • HeLa Cells
  • Humans
  • Isodon / chemistry
  • Molecular Conformation
  • Plants, Medicinal / chemistry

Substances

  • Diterpenes
  • maoecrystal V